We patiently compiled a comprehensive list of interventional clinical trials based on human pluripotent stem cells (both ES and iPS cells). You can sort this list by organ, indication, date, number of patients, clinical phase. Enjoy ! 🙂
Induced hPSCs are often touted as an infinite source of cells for research, disease modelling, and therapeutic applications. Being adherent cells, hPSCs have originally been cultured as 2D colonies in Petri dishes or T-flasks. However, despite their apparent unlimited proliferation capacity, hPSCs only exist for a few days in vivo and do not grow as 2D colonies. In vivo, pluripotency (here restricted to human primed pluripotency) is only observed during the second week of human development, and exclusively within 3D epithelialized arrangements of cells.