{"id":2630,"date":"2023-03-07T14:27:59","date_gmt":"2023-03-07T14:27:59","guid":{"rendered":"https:\/\/preprod.treefrog.fr\/stemcelljungle\/?p=2630"},"modified":"2023-03-07T14:38:24","modified_gmt":"2023-03-07T14:38:24","slug":"new-paper-in-biomaterials-describes-massive-hipsc-expansion-in-10l-bioreactors","status":"publish","type":"post","link":"https:\/\/preprod.treefrog.fr\/stemcelljungle\/new-paper-in-biomaterials-describes-massive-hipsc-expansion-in-10l-bioreactors\/","title":{"rendered":"New paper in Biomaterials describes massive hiPSC expansion in 10L bioreactors"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2630\" class=\"elementor elementor-2630\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c8317f4 elementor-section-boxed elementor-section-height-default elementor-section-height-default parallax_section_no qode_elementor_container_no\" data-id=\"c8317f4\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a42feb5\" data-id=\"a42feb5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ac359f9 elementor-widget elementor-widget-text-editor\" data-id=\"ac359f9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Entitled &#8220;<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0142961223000418\">Engineering 3D micro-compartments for highly efficient and scale-independent expansion of human pluripotent stem cells in bioreactors<\/a>&#8221; this paper highlights:<\/p><p>\u00a0<\/p><p>&#8211; <strong>Biomimetic features<\/strong> of C-Stem\u2122-generated capsules, allowing for in vivo-like hiPSC self-organization into <a href=\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/release-of-the-white-paper-on-the-hipsc-lumenized-rosette\/\">lumenized rosettes<\/a><\/p><p>\u00a0<\/p><p>&#8211; <strong>Unprecedented exponential hiPSC growth in 10L bioreactors:<\/strong> &gt;275-fold within 6.5 days, with high reproducibility<\/p><p>\u00a0<\/p><p>&#8211; <strong>Maintenance of cell quality<\/strong> (pluripotency &amp; genonomic integrity) throughout massive expansion\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e292863 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"e292863\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0142961223000418\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read the paper (open access)<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Entitled \u201cEngineering 3D micro-compartments for highly efficient and scale-independent expansion of human pluripotent stem cells in bioreactors\u201d this paper highlights: Biomimetic features of C-Stem\u2122-generated capsules, allowing for in vivo-like hiPSC self-organization into lumenized rosettes \/ Unprecedented exponential hiPSC growth in 10L bioreactors: >275-fold within 6.5 days, with high reproducibility \/ Maintenance of cell quality (pluripotency &#038; genonomic integrity) throughout massive expansion <\/p>\n","protected":false},"author":1,"featured_media":2632,"comment_status":"open","ping_status":"closed","sticky":true,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[9],"tags":[],"aioseo_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>New paper in Biomaterials describes massive hiPSC expansion in 10L bioreactors - Stem Cells &amp; Cell Therapy Blog I In the Stem Cell Jungle I iPSCs I TreeFrog Therapeutics<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New paper in Biomaterials describes massive hiPSC expansion in 10L bioreactors - Stem Cells &amp; Cell Therapy Blog I In the Stem Cell Jungle I iPSCs I TreeFrog Therapeutics\" \/>\n<meta property=\"og:description\" content=\"Entitled \u201cEngineering 3D micro-compartments for highly efficient and scale-independent expansion of human pluripotent stem cells in bioreactors\u201d this paper highlights: Biomimetic features of C-Stem\u2122-generated capsules, allowing for in vivo-like hiPSC self-organization into lumenized rosettes \/ Unprecedented exponential hiPSC growth in 10L bioreactors: &gt;275-fold within 6.5 days, with high reproducibility \/ Maintenance of cell quality (pluripotency &amp; genonomic integrity) throughout massive expansion\" \/>\n<meta property=\"og:url\" content=\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/new-paper-in-biomaterials-describes-massive-hipsc-expansion-in-10l-bioreactors\/\" \/>\n<meta property=\"og:site_name\" content=\"Stem Cells &amp; Cell Therapy Blog I In the Stem Cell Jungle I iPSCs I TreeFrog Therapeutics\" \/>\n<meta property=\"article:published_time\" content=\"2023-03-07T14:27:59+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-07T14:38:24+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/wp-content\/uploads\/sites\/5\/2023\/03\/Biomaterials-paper-Engineering-3D-micro-compartments-for-highly-efficient-and-scale-independent-expansion-human-pluripotent-stem-cells-in-bioreactors.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"768\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Piergueritona\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@treefrogtx\" \/>\n<meta name=\"twitter:site\" content=\"@treefrogtx\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/new-paper-in-biomaterials-describes-massive-hipsc-expansion-in-10l-bioreactors\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/new-paper-in-biomaterials-describes-massive-hipsc-expansion-in-10l-bioreactors\/\"},\"author\":{\"name\":\"Piergueritona\",\"@id\":\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/#\/schema\/person\/ab868aec652cf07c221b48c1dc91a220\"},\"headline\":\"New paper in Biomaterials describes massive hiPSC expansion in 10L bioreactors\",\"datePublished\":\"2023-03-07T14:27:59+00:00\",\"dateModified\":\"2023-03-07T14:38:24+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/new-paper-in-biomaterials-describes-massive-hipsc-expansion-in-10l-bioreactors\/\"},\"wordCount\":79,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/#organization\"},\"articleSection\":[\"Articles\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/new-paper-in-biomaterials-describes-massive-hipsc-expansion-in-10l-bioreactors\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/new-paper-in-biomaterials-describes-massive-hipsc-expansion-in-10l-bioreactors\/\",\"url\":\"https:\/\/preprod.treefrog.fr\/stemcelljungle\/new-paper-in-biomaterials-describes-massive-hipsc-expansion-in-10l-bioreactors\/\",\"name\":\"New paper in Biomaterials describes massive hiPSC expansion in 10L bioreactors - Stem Cells &amp; 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