{"id":2478,"date":"2021-01-20T14:47:00","date_gmt":"2021-01-20T14:47:00","guid":{"rendered":"https:\/\/preprod.treefrog.fr\/stemcelljungle\/?p=2478"},"modified":"2023-03-03T14:56:36","modified_gmt":"2023-03-03T14:56:36","slug":"stem-cell-therapy-for-diabetes-allogeneic-vs-autologous","status":"publish","type":"post","link":"https:\/\/preprod.treefrog.fr\/stemcelljungle\/stem-cell-therapy-for-diabetes-allogeneic-vs-autologous\/","title":{"rendered":"Stem Cell Therapy for Diabetes: Allogeneic vs Autologous ?"},"content":{"rendered":"\t\t
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\n\t\t\t\t\t\t\t\t\tAlbert Hwa explains why the Joslin’s CCTD launched an autologous cell therapy program, and discusses the promise of allogeneic cell therapies for Diabetes.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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For us, first of all, we want to use the setting of autologous therapy to just do a more simple validation to show that the cells are safe and effective.<\/p>

So in order to make it simple, we specifically tried to go into a patient population that doesn’t have autoimmmunity against the islet cells.<\/p>

We have selected patients who had pancreatectomies, and they didn’t seem to have any islet autoimmunity.<\/p>

I think to widely apply the therapy… you cannot argue with the business case of using allogeneic cell source.<\/p>

That’s how you are able to produce trillions and trillions of cells.<\/p>

But then immunology – and immune reaction – is still the biggest hurdle.<\/p>

I think gene editing has a lot of promise, and I’m hoping it will work out.<\/p>

I think autologous, at the current timepoint, unless we can significantly lower the cost of doing this personalized therapy, I think it will be really difficult to do it widely, for all the patients.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tWatch full video<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Albert Hwa explains why the Joslin’s CCTD launched an autologous cell therapy program, and discusses the promise of allogeneic cell therapies for Diabetes.<\/p>\n","protected":false},"author":1,"featured_media":2479,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[],"aioseo_notices":[],"yoast_head":"\nStem Cell Therapy for Diabetes: Allogeneic vs Autologous ? - Stem Cells & Cell Therapy Blog I In the Stem Cell Jungle I iPSCs I TreeFrog Therapeutics<\/title>\n<meta name=\"description\" content=\"Albert Hwa explains why the Joslin's CCTD launched an autologous cell therapy program, and discusses the promise of allogeneic cell therapies for Diabetes.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Stem Cell Therapy for Diabetes: Allogeneic vs Autologous ? 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