{"id":4279,"date":"2022-11-02T10:54:36","date_gmt":"2022-11-02T10:54:36","guid":{"rendered":"https:\/\/preprod.treefrog.fr\/fr\/?p=4279"},"modified":"2022-11-07T09:09:33","modified_gmt":"2022-11-07T09:09:33","slug":"nouvel-encapsulateur-aux-normes-bpf-interview-de-notre-coo-michael-lanero-fidalgo","status":"publish","type":"post","link":"https:\/\/preprod.treefrog.fr\/fr\/nouvel-encapsulateur-aux-normes-bpf-interview-de-notre-coo-michael-lanero-fidalgo\/","title":{"rendered":"Nouvel encapsulateur aux normes BPF : interview de Michael LANERO FIDALGO, Directeur des op\u00e9rations"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4279\" class=\"elementor elementor-4279\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-86706bc elementor-section-boxed elementor-section-height-default elementor-section-height-default parallax_section_no qode_elementor_container_no\" data-id=\"86706bc\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-177c1de\" data-id=\"177c1de\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cba2c4b elementor-widget elementor-widget-video\" data-id=\"cba2c4b\" data-element_type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/youtu.be\\\/7WxHnvF9wMc&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-11dcb79 elementor-widget elementor-widget-text-editor\" data-id=\"11dcb79\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span lang=\"EN-US\">\u00ab\u00a0Cet encapsulateur aux normes BPF (Bonnes Pratiques de Fabrication) est notre ticket d&rsquo;entr\u00e9e vers la clinique\u00a0\u00bb r\u00e9sume&nbsp;<\/span>Michael Lanero Fidalgo, Directeur des Op\u00e9rations de TreeFrog Therapeutics (communiqu\u00e9 de presse complet sur la plateforme C-Stem\u2122 BPF <a href=\"https:\/\/preprod.treefrog.fr\/treefrog-therapeutics-moves-to-gmp-manufacturing-with-cell-encapsulation-device-delivered-by-invetech\/\">ici<\/a>).<\/p>\n<h5><strong><span lang=\"EN-US\">La plateforme BPF de TreeFrog en bref<\/span><\/strong><\/h5>\n<p><span lang=\"EN-US\"><strong>&#8211; Encapsulation de cellules \u00e0 haut d\u00e9bit :<\/strong> &gt;1,000 capsules par seconde (les capsules sont con\u00e7ues pour fournir aux cellules un microenvironnement biomim\u00e9tique prot\u00e9g\u00e9 des stress hydrodynamiques externes)<br><\/span><\/p>\n<p><span lang=\"EN-US\"><strong>&#8211; Ensemencement de bior\u00e9acteurs de 200mL \u00e0 10L pour :<\/strong><\/span><\/p>\n<p><span lang=\"EN-US\"><strong>#1<\/strong> L&rsquo;expansion de cellules souches \u00e0 grande \u00e9chelle (amplification des <span style=\"background-color: #ffffff;\">cellules souches pluripotentes induites (CSPi)<\/span>&nbsp;&gt;250x\/semaine<\/span>&nbsp;avec une qualit\u00e9 cellulaire de tr\u00e8s haut niveau)<\/p>\n<p><span lang=\"EN-US\"><strong>#2<\/strong> La diff\u00e9renciation de cellules souches en microtissus 3D fonctionnels pr\u00eats-\u00e0-transplanter.<\/span><\/p>\n<p><span lang=\"EN-US\"><strong>&#8211; Dissolution de l&rsquo;enveloppe d&rsquo;alginate facile et rapide<\/strong> pour lib\u00e9rer le contenu cellulaire<\/span><\/p>\n<p><\/p>\n<h5><span lang=\"EN-US\"><strong>Prochaines \u00e9tapes :<\/strong><\/span><\/h5><p><span lang=\"EN-US\"><strong>2023 : <\/strong><\/span><strong>transfert<\/strong> \u00e0 une soci\u00e9t\u00e9 de d\u00e9veloppement et de fabrication sous contrat (CDMO) pour produire des lots de qualit\u00e9 clinique pour le programme de th\u00e9rapie cellulaire de TreeFrog contre la maladie de Parkinson.<\/p>\n<p><span lang=\"EN-US\"><strong>2023: 3 nouvelles machines<\/strong> aux normes BPF seront livr\u00e9es pour soutenir les programmes internes de TreeFrog en m\u00e9decine r\u00e9g\u00e9n\u00e9rative et immuno-oncologie.<\/span><\/p>\n<p><span lang=\"EN-US\"><strong>&nbsp;2024 :<\/strong> Lancement des premiers essais cliniques sur l&rsquo;homme pour la maladie de Parkinson.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-56a7fd0 elementor-section-boxed elementor-section-height-default elementor-section-height-default parallax_section_no qode_elementor_container_no\" data-id=\"56a7fd0\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fbe7d76\" data-id=\"fbe7d76\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2bcaf3b elementor-align-center elementor-widget elementor-widget-button\" data-id=\"2bcaf3b\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md\" href=\"https:\/\/preprod.treefrog.fr\/3-phd-students-from-kings-college-london-win-the-100000-stem-cell-spaceshot-grant\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Lire le Communiqu\u00e9 de Presse complet<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>https:\/\/youtu.be\/7WxHnvF9wMc \u00ab\u00a0Cet encapsulateur aux normes BPF (Bonnes Pratiques de Fabrication) est notre ticket d&rsquo;entr\u00e9e vers la clinique\u00a0\u00bb r\u00e9sume&nbsp;Michael Lanero Fidalgo, Directeur des Op\u00e9rations de TreeFrog Therapeutics (communiqu\u00e9 de presse complet sur la plateforme C-Stem\u2122 BPF ici). La plateforme BPF de TreeFrog en bref &#8211; Encapsulation&#8230;<\/p>\n","protected":false},"author":1,"featured_media":4280,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[15,19,13],"tags":[],"aioseo_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Nouvel encapsulateur aux normes BPF : interview de Michael LANERO FIDALGO, Directeur des op\u00e9rations - TreeFrog Therapeutics I Les th\u00e9rapies cellulaires pour tous<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nouvel encapsulateur aux normes BPF : interview de Michael LANERO FIDALGO, Directeur des op\u00e9rations - TreeFrog Therapeutics I Les th\u00e9rapies cellulaires pour tous\" \/>\n<meta property=\"og:description\" content=\"https:\/\/youtu.be\/7WxHnvF9wMc \u00ab\u00a0Cet encapsulateur aux normes BPF (Bonnes Pratiques de Fabrication) est notre ticket d&rsquo;entr\u00e9e vers la clinique\u00a0\u00bb r\u00e9sume&nbsp;Michael Lanero Fidalgo, Directeur des Op\u00e9rations de TreeFrog Therapeutics (communiqu\u00e9 de presse complet sur la plateforme C-Stem\u2122 BPF ici). 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